Steroid diversification by multicomponent reactions

• Leslie Reguera,
• Cecilia I. Attorresi,
• Javier A. Ramírez and
• Daniel G. Rivera

Beilstein J. Org. Chem. 2019, 15, 1236–1256, doi:10.3762/bjoc.15.121

• library of androstanic derivatives 21 (Figure 2B) and their reduced analogues bearing the 3β-hydroxy group were biologically tested showing antifungal activity against Fusarium virguliforme and Fusarium solani. The generation of this compound library suffered from the formation of the Passerini reaction

The direct oxidative diene cyclization and related reactions in natural product synthesis

• Juliane Adrian,
• Leona J. Gross and
• Christian B. W. Stark

Beilstein J. Org. Chem. 2016, 12, 2104–2123, doi:10.3762/bjoc.12.200

• isolated from the mould fungus Fusarium solani as a phytotoxin against barnyardgrass and duckweed in 1996 [30]. The Donohoe group presented a total synthesis in 2003 using an Os(VIII)-catalyzed oxidative cyclization as the key step [31] (Scheme 4). Several other total syntheses of that natural product did

Volatile organic compounds produced by the phytopathogenic bacterium Xanthomonas campestris pv. vesicatoria 85-10

• Teresa Weise,
• Marco Kai,
• Anja Gummesson,
• Armin Troeger,
• Stephan von Reuß,
• Silvia Piepenborn,
• Francine Kosterka,
• Martin Sklorz,
• Ralf Zimmermann,
• Wittko Francke and
• Birgit Piechulla

Beilstein J. Org. Chem. 2012, 8, 579–596, doi:10.3762/bjoc.8.65

• bacteria were different for growth on media (nutrient broth) with or without glucose. Keywords: Aspergillus nidulans; Fusarium solani; growth inhibition and promotion; methylketones; 10-methylundecan-2-one; Rhizoctonia solani; volatile organic compound (VOC); Xanthomonas campestris pv. vesicatoria

• other organisms, three fungi, Aspergillus nidulans, Fusarium solani and Rhizoctonia solani, were cocultivated with X. c. pv. vesicatoria 85-10 in compartmentalized Petri dishes (Figure 1). This ensures that only volatiles can diffuse between the compartments to act on the fungal test organisms. Since it

• . Interestingly, Fusarium solani was only weakly influenced by the volatiles of X. c. pv. vesicatoria 85-10, indicating species-specific reactions. Similar results were obtained when ten different rhizobacteria were tested with various fungi [27]. Most of the tested fungi, including R. solani, Verticillium